Relationship between physical exercise load and return-to-work in female breast cancer survivors Systematic review
Article Sidebar
Main Article Content
Abstract
Introduction: Evidence has shown physical exercise leads health benefits in breast cancer survivors, for example reducing return-to-work (RTW) time. However, what exercise component has (if any) the greatest impact on the recovery time after breast cancer. The aim of this study is to determine the exercise load variables (type, frequency, intensity, exercise time, volume, density and progression) that are best associated with recovery time in female breast cancer survivors (measured as time off work). Methods: In this systematic review, we included experimental, cohort, and observational studies of female breast cancer survivors engaging in physical exercise programs. We searched PubMed, Web of Science, Sport Discus, and Scopus (Sep 2021-Sep 2022) using the PICOS strategy and PRISMA 2020 guidelines. Studies were independently screened and data extracted into a database, focusing on exercise variables association with return-to-work time. Methodological quality was assessed using ROB 2.0, considering study design, intervention details, and bias risk. Results: Following screening, seven studies were included in this review, with five defining a minimum of one exercise component. Two studies specified frequency and density, while three defined the type, frequency, volume, intensity, density, and progression of interventions. No study found a direct correlation between exercise components and RTW time. Conclusions: In the literature reviewed in this systematic review, it is not possible to identify which exercise variable(s) have the strongest correlation with RTW outcomes. The existing studies demonstrate a lack of comprehensive intervention descriptions, limiting our understanding of the distinct exercise components and their potential effects on RTW results.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Funding data
-
Agència de Gestió d'Ajuts Universitaris i de Recerca
Grant numbers PRE/2835/2020
References
Algeo, N., Bennett, K., & Connolly, D. (2021). Rehabilitation interventions to support return to work for women with breast cancer: a systematic review and meta-analysis. BMC Cancer, 21(1). https://doi.org/10.1186/s12885-021-08613-x
Androulakis-Korakakis, P., Fisher, J. P., & Steele, J. (2020). The Minimum Effective Training Dose Required to Increase 1RM Strength in Resistance-Trained Men: A Systematic Review and Meta-Analysis. Sports Medicine, 50(4), 751-765. https://doi.org/10.1007/s40279-019-01236-0
Baumann, F. T., Reike, A., Hallek, M., Wiskemann, J., & Reimer, V. (2018). Does Exercise Have a Preventive Effect on Secondary Lymphedema in Breast Cancer Patients Following Local Treatment? - A Systematic Review. Breast Care, 13(5), 380-385. https://doi.org/10.1159/000487428
Berglund, G., Bolund, C., Gustafsson, U. L., & Sjödén, P. O. (1994). One-year follow-up of the "Starting Again" Group rehabilitation programme for cancer patients. European Journal of Cancer, 30(12), 1744-1751. https://doi.org/10.1016/0959-8049(94)00330-8
Bicego, D., Brown, K., Ruddick, M., Storey, D., Wong, C., & Harris, S. R. (2009). Effects of Exercise on Quality of Life in Women Living with Breast Cancer: A Systematic Review. The Breast Journal, 15(1), 45-51. https://doi.org/10.1111/j.1524-4741.2008.00670.x
Björneklett, H. G., Rosenblad, A., Lindemalm, C., Ojutkangas, M. L., Letocha, H., Strang, P., & Bergkvist, L. (2013). A randomized controlled trial of support group intervention after breast cancer treatment: Results on sick leave, health care utilization and health economy. Acta Oncologica, 52(1), 38-47. https://doi.org/10.3109/0284186X.2012.734921
Bolam, K. A., Mijwel, S., Rundqvist, H., & Wengström, Y. (2019). Two-year follow-up of the OptiTrain randomised controlled exercise trial. Breast Cancer Research and Treatment, 175(3), 637-648. https://doi.org/10.1007/s10549-019-05204-0
Borjesson, M., & Sundberg, C. J. (2013). FYSS (physical activity book for prevention and treatment): Behavioural change also for the physician? British Journal of Sports Medicine, 47. https://doi.org/10.1136/bjsports-2013-092940
Campbell, K. L., Winters-Stone, K. M., Wiskemann, J., May, A. M., Schwartz, A. L., Courneya, K. S., Zucker, D. S., Matthews, C. E., Ligibel, J. A., Gerber, L. H., Morris, G. S., Patel, A. V., Hue, T. F., Perna, F. M., & Schmitz, K. H. (2019). Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable. Medicine and Science in Sports and Exercise, 51(11), 2375-2390. https://doi.org/10.1249/MSS.0000000000002116
Caspersen, C. J., Powell, K. E., & Christenson, G. M. (1985). Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Reports (Washington, D.C. : 1974), 100(2), 126-131.
Dalager, T., Bredahl, T. G. V., Pedersen, M. T., Boyle, E., Andersen, L. L., & Sjøgaard, G. (2015). Does training frequency and supervision affect compliance, performance and muscular health? A cluster randomized controlled trial. Manual Therapy, 20(5), 657-665. https://doi.org/10.1016/j.math.2015.01.016
Di Blasio, A., Morano, T., Bucci, I., Di Santo, S., D'Arielli, A., Castro, C. G., Cugusi, L., Cianchetti, E., Napolitano, G., D'Arielli, A., Castro, C. G., Cugusi, L., Cianchetti, E., & Napolitano, G. (2016). Physical exercises for breast cancer survivors: effects of 10 weeks of training on upper limb circumferences. Journal of Physical Therapy Science, 28(10), 2778-2784. https://doi.org/10.1589/jpts.28.2778
Escriche-Escuder, A., Casaña, J., & Cuesta-Vargas, A. I. (2020). Load progression criteria in exercise programmes in lower limb tendinopathy: a systematic review. BMJ Open, 10(11), e041433. https://doi.org/10.1136/bmjopen-2020-041433
Ferguson, B. (2014). ACSM's Guidelines for Exercise Testing and Prescription 9th Ed. 2014. In The Journal of the Canadian Chiropractic Association (Vol. 58, Issue 3, p. 328).
González-Peris M, Peirau X, Roure E, & Violán M. (2022). Guia de prescripció d'exercici físic per a la salut. 2a ed. Barcelona: Generalitat de Catalunya; 2022. 132.
Goodman, S., Fanelli, D., & Ioannidis, J. (2016). What does research reproducibility mean? Science Translational Medicine, 8, 341ps12-341ps12. https://doi.org/10.1126/scitranslmed.aaf5027
Heredia-Elvar, J. R., Donate, F. I., Chulvi-Medrano, I., Costa, M. R., & Soro, J. (n.d.). Heredia Elvar, JR. Chulvi Medrano, I. Isidro Donate, F. Soro, J. Costa, MR (2007) Determinación de la Carga de Entrenamiento para la Mejora de la Fuerza orientada a la Salud (Fitness Muscular). PubliCE. Retrieved from [Accessed March 05, 2024]: https://journal.onlineeducation.center/api-oas/v1/articles/sa-K57cfb27188271/export-pdf/determinacion-de-la-carga-de-entrenamiento-para-la-mejora-de-la-fuerza-orientada-a-la-salud-fitness-muscular-794
Herrero, F., San Juan, A. F., Fleck, S. J., Foster, C., & Lucia, A. (2007). Effects of detraining on the functional capacity of previously trained breast cancer survivors. International Journal of Sports Medicine, 28(3), 257-264. https://doi.org/10.1055/s-2006-924348
Higgins, J. P., Savović, J., Page, M. J., & Sterne, J. A. C. (2019). RoB 2 Guidance: Parallel Trial. The Cochrane Collaboration, July, 1-24. Retrieved from [Accessed March 05, 2024]: https://methods.cochrane.org/bias/resources/rob-2-revised-cochrane-risk-bias-tool-randomized-trials
Hurst, C., Robinson, S. M., Witham, M. D., Dodds, R. M., Granic, A., Buckland, C., De Biase, S., Finnegan, S., Rochester, L., Skelton, D. A., & Sayer, A. A. (2022). Resistance exercise as a treatment for sarcopenia: prescription and delivery. Age and Ageing, 51(2). https://doi.org/10.1093/ageing/afac003
Impellizzeri, F. M., Menaspà, P., Coutts, A. J., Kalkhoven, J., & Menaspà, M. J. (2020). Training Load and Its Role in Injury Prevention, Part I: Back to the Future. Journal of Athletic Training, 55(9), 885-892. https://doi.org/10.4085/1062-6050-500-19
Irwin, M. L. (2009). Physical activity interventions for cancer survivors. British Journal of Sports Medicine, 43(1), 32-38. https://doi.org/10.1136/bjsm.2008.053843
Jong, M. C., Boers, I., Schouten Van Der Velden, A. P., Meij, S. Van Der, Göker, E., Timmer-Bonte, A. N. J. H., & Van Wietmarschen, H. A. (2018). A Randomized Study of Yoga for Fatigue and Quality of Life in Women with Breast Cancer Undergoing (Neo) Adjuvant Chemotherapy. Journal of Alternative and Complementary Medicine, 24(9-10), 942-953. https://doi.org/10.1089/acm.2018.0191
Juvet, L. K., Thune, I., Elvsaas, I. K. Ø., Fors, E. A., Lundgren, S., Bertheussen, G., Leivseth, G., & Oldervoll, L. M. (2017). The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis. In Breast (Vol. 33, pp. 166-177). Elsevier. https://doi.org/10.1016/j.breast.2017.04.003
Lahart, I. M., Metsios, G. S., Nevill, A. M., & Carmichael, A. R. (2018). Physical activity for women with breast cancer after adjuvant therapy. Cochrane Database of Systematic Reviews, 1(1), CD011292. https://doi.org/10.1002/14651858.CD011292.pub2
Magal, M., & Scheinowitz, M. (2018). Benefits and Risks Associated with Physical Activity. In D. Riebe, J. K. Ehrman, G. Liguori, & M. Magal (Eds.), ACSM's guidelines for exercise testing and prescription (10th ed., pp. 1-21). Wolters Kluwer.
Matthews, E. E., Janssen, D. W., Djalilova, D. M., & Berger, A. M. (2018). Effects of Exercise on Sleep in Women with Breast Cancer: A Systematic Review. Sleep Medicine Clinics, 13(3), 395-417. https://doi.org/10.1016/j.jsmc.2018.04.007
Mijwel, S., Jervaeus, A., Bolam, K. A., Norrbom, J., Bergh, J., Rundqvist, H., & Wengström, Y. (2019). High-intensity exercise during chemotherapy induces beneficial effects 12 months into breast cancer survivorship. Journal of Cancer Survivorship, 13(2), 244-256. https://doi.org/10.1007/s11764-019-00747-z
Pedersen, B. K., & Saltin, B. (2015). Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases. Scandinavian Journal of Medicine & Science in Sports, 25, 1-72. https://doi.org/10.1111/sms.12581
Ramírez-Vélez, R., Izquierdo, M., Castro-Astudillo, K., Medrano-Mena, C., Monroy-Díaz, A. L., Castellanos-Vega, R. del P., Triana-Reina, H. R., & Correa-Rodríguez, M. (2020). Weight Loss after 12 Weeks of Exercise and/or Nutritional Guidance Is Not Obligatory for Induced Changes in Local Fat/Lean Mass Indexes in Adults with Excess of Adiposity. Nutrients, 12(8), 2231. https://doi.org/10.3390/nu12082231
Rogers, L. Q., Hopkins-Price, P., Vicari, S., Pamenter, R., Courneya, K. S., Markwell, S., Verhulst, S., Hoelzer, K., Naritoku, C., Jones, L., Dunnington, G., Lanzotti, V., Wynstra, J., Shah, L., Edson, B., Graff, A., & Lowy, M. (2009). A randomized trial to increase physical activity in breast cancer survivors. Medicine and Science in Sports and Exercise, 41(4), 935-946. https://doi.org/10.1249/MSS.0b013e31818e0e1b
Santos, C. M. da C., Pimenta, C. A. de M., & Nobre, M. R. C. (2007). The PICO strategy for the research question construction and evidence search. Revista Latino-Americana de Enfermagem, 15(3), 508-511. https://doi.org/10.1590/S0104-11692007000300023
Savard, J., Ivers, H., Villa, J., Caplette-Gingras, A., & Morin, C. M. (2011). Natural course of insomnia comorbid with cancer: an 18-month longitudinal study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 29(26), 3580-3586. https://doi.org/10.1200/JCO.2010.33.2247
Schoenfeld, B. J., Contreras, B., Krieger, J., Grgic, J., Delcastillo, K., Belliard, R., & Alto, A. (2019). Resistance Training Volume Enhances Muscle Hypertrophy but Not Strength in Trained Men. Medicine & Science in Sports & Exercise, 51(1), 94-103. https://doi.org/10.1249/MSS.0000000000001764
Schoenfeld, B. J., Ogborn, D., & Krieger, J. W. (2016). Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis. Sports Medicine, 46(11), 1689-1697. https://doi.org/10.1007/s40279-016-0543-8
Schutz, S., Aidar, F. J., Souza, R. L. M., dos Santos, J. L., Voltarelli, F. A., Vieira Junior, R. C., Soares, N. M. M., & Marçal, A. C. (2021). Different Methods of Physical Training Applied to Women Breast Cancer Survivors: A Systematic Review. Frontiers in Physiology, 12. https://doi.org/10.3389/fphys.2021.639406
Tamminga, S. J., De Boer, A. G. E. M., Verbeek, J. H. A. M., & Frings-Dresen, M. H. W. (2010). Return-to-work interventions integrated into cancer care: A systematic review. Occupational and Environmental Medicine, 67(9), 639-648. https://doi.org/10.1136/oem.2009.050070
The American Cancer Society. (2019). The economic burden of cancer. The Economic Burden of Cancer. Retrieved from [Accessed March 05, 2024]: https://canceratlas.cancer.org/taking-action/economic-burden/
Van Waart, H., Stuiver, M. M., Van Harten, W. H., Geleijn, E., Kieffer, J. M., Buffart, L. M., De Maaker-Berkhof, M., Boven, E., Schrama, J., Geenen, M. M., Meerum Terwogt, J. M., Van Bochove, A., Lustig, V., Van Den Heiligenberg, S. M., Smorenburg, C. H., Hellendoorn-van Vreeswijk, J. A. J. H., Sonke, G. S., & Aaronson, N. K. (2015). Effect of low-intensity physical activity and moderate- to high-intensity physical exercise during adjuvant chemotherapy on physical fitness, fatigue, and chemotherapy completion rates: Results of the PACES randomized clinical trial. Journal of Clinical Oncology, 33(17), 1918-1927. https://doi.org/10.1200/JCO.2014.59.1081
Wild CP, W. E. y S. B. (2020). World Cancer Report: Cancer Research for Cancer Prevention. International Agency for Research on Cancer. Retrieved from [Accessed March 05, 2024]: http://publications.iarc.fr/586
Wilson, T. N., Nambiema, A., Porro, B., Descatha, A., Aublet-Cuvelier, A., Evanoff, B., & Roquelaure, Y. (2023). Effectiveness of Physical Activity Interventions on Return to Work After a Cancer Diagnosis: A Systematic Review and Meta-analysis. Journal of Occupational Rehabilitation, 33(1), 4-19. https://doi.org/10.1007/s10926-022-10052-9