Protocol of the oncological physical exercise unit of the province of Alicante

Main Article Content

José Antonio Pérez-Turpin
Lucía Gil Herrero
Ana Isabel González Márquez
Carlos Elvira Aranda
María José Gomis-Gomis
Juan Lledó Quirant
Xesús Pena-Pérez


The Oncological Physical Exercise Unit (UEFO) of the province of Alicante, was created by the Spanish Association Against Cancer and Kinetic Performance (EBT of the University of Alicante) with the aim of promoting healthcare, educational and research activities focused on the benefits of physical exercise in oncological disease and its impact on the quality of life of patients, and together with the better tolerance of oncological treatments. The Unit is made up of members of the GICAFD research group of the University of Alicante and professionals with professional experience in different areas of health and physical exercise.

Article Details

How to Cite
Pérez-Turpin, J. A., Gil Herrero, L., González Márquez, A. I., Elvira Aranda, C., Gomis-Gomis, M. J., Lledó Quirant, J., & Pena-Pérez, X. (2024). Protocol of the oncological physical exercise unit of the province of Alicante. Physical Activity, Exercise and Cancer, 1(1), 23–30.
Physical activity and exercise during cancer treatments
Author Biographies

Lucía Gil Herrero, Spanish Association Against Cancer

Physical Well-being Unit. Madrid Regional Council.

Ana Isabel González Márquez, Spanish Association Against Cancer

Physical Well-being Unit. Madrid Regional Council.


Arrieta, H., Astrugue, C., Regueme, S., Durrieu, J., Maillard, A., Rieger, A., Terrebonne, E., Laurent, C., Maget, B., Servent, V., Lavau-Denès, S., Dauba, J., Fonck, M., Thiébaut, R., & Bourdel-Marchasson, I. (2019). Effects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: A randomized multicentre trial. Journal of Cachexia, Sarcopenia and Muscle, 10(2), 287-297.

Bortolozo, H. I., Derchain, S., Vechin, F. C., Maginador, G. F., Santos, I. S., Torresan, R., De Nazaré Silva dos Santos, P., Sarian, L. O., & Conceição, M. S. (2021). Aerobic Fitness is a Predictor of Body Composition in Women With Breast Cancer at Diagnosis. Clinical Breast Cancer, 21(3), e245-e251.

Campbell, K. L., Winters-Stone, K. M., Wiskemann, J., May, A. M., Schwartz, A. L., Courneya, K. S., Zucker, D. S., Matthews, C. E., Ligibel, J. A., Gerber, L. H., Morris, G. S., Patel, A. V., Hue, T. F., Perna, F. M., & Schmitz, K. H. (2019). Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable. Medicine & science in sports & exercise, 51(11), 2375-2390.

Cella, D., Hernandez, L., Bonomi, A. E., Corona, M., Vaquero, M., Shiomoto, G., & Baez, L. (1998). Spanish language translation and initial validation of the functional assessment of cancer therapy quality-of-life instrument. Medical care, 36(9), 1407-1418.

Cella, D. F., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., Bonomi, A., Silberman, M., Yellen, S. B., Winicour, P., & Brannon, J. (1993). The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 11(3), 570-579.

Dalise, S., Tropea, P., Galli, L., Sbrana, A., & Chisari, C. (2020). Muscle function impairment in cancer patients in pre-cachexia stage. European journal of translational myology, 30(2), 8931.

de Lima, C., Alves, L. E., Iagher, F., Machado, A. F., Bonatto, S. J., Kuczera, D., de Souza, C. F., Pequito, D. C., Muritiba, A. L., Nunes, E. A., & Fernandes, L. C. (2008). Anaerobic exercise reduces tumor growth, cancer cachexia and increases macrophage and lymphocyte response in Walker 256 tumor-bearing rats. European journal of applied physiology, 104(6), 957-964.

Desbiens, C., Filion, M., Brien, M., Hogue, J., Laflamme, C., & Lemieux, J. (2017). Impact of physical activity in group versus individual physical activity on fatigue in patients with breast cancer: A pilot study. The Breast, 35, 8-13.

Fernández-Lao, C., Cantarero-Villanueva, I., Ariza-Garcia, A., Courtney, C Fernández-De-LasPeñas, C., & Arroyo-Morales (2021). Water versus land-based multimodal exercise program effects on body composition in breast cancer survivors: a controlled clinical trial. Support Care Cancer 21, 521-530.

Gil Herrero, L., Courneya, K. S., McNeely, M. L., Castellanos, M., González Marquez, A. I., Pollan, M., & Casla-Barrio, S. (2022). Effects of a Clinical Exercise Program on Health-Related Fitness and Quality of Life in Spanish Cancer Patients Receiving Adjuvant Therapy. Integrative Cancer Therapies, 21

Gil Herrero, L., McNeely, M. L., Courneya, K. S., Castellanos Montealegre, M., González Marquez, A. I., Pollan Santamaría, M., & Casla Barrio, S. (2022). Safety, feasibility, and effectiveness of implementing supervised exercise into the clinical care of individuals with advanced cancer. Clinical Rehabilitation, 36(12):1666-1678.

Gopalakrishna, A., Longo, T. A., Fantony, J. J., Harrison, M. R., & Inman, B. A. (2017). Physical activity patterns and associations with health-related quality of life in bladder cancer survivors. Urologic Oncology: Seminars and Original Investigations, 35(9), 540.e1-540.e6.

Gould, D. W., Lahart, I., Carmichael, A. R., Koutedakis, Y., & Metsios G. S. (2013). Cancer cachexia prevention via physical exercise: molecular mechanisms. J Cachexia Sarcopenia Muscle 4, 111-124.

Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., Bonsel, G., & Badia, X. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 20(10), 1727-1736.

Hooshmand Moghadam, B., Golestani, F., Bagheri, R., Cheraghloo, N., Eskandari, M., Wong, A., Nordvall, M., Suzuki, K., & Pournemati, P. (2021). The Effects of High-Intensity Interval Training vs. Moderate-Intensity Continuous Training on Inflammatory Markers, Body Composition, and Physical Fitness in Overweight/Obese Survivors of Breast Cancer: A Randomized Controlled Clinical Trial. Cancers, 13(17), 4386.

Jung, G. H., Kim, J. H., & Chung, M. S. (2020). Changes in weight, body composition, and physical activity among patients with breast cancer under adjuvant chemotherapy. European Journal of Oncology Nursing, 44, 101680.

Lewis, C., Xun, P. & He, K. (2014). Physical activity in relation to quality of life in newly diagnosed colon cancer patients: a 24-month follow-up. Quality Life Research 23, 2235-2246

Maginador, G., Lixandrão, M. E., Bortolozo, H. I., Vechin, F. C., Sarian, L. O., Derchain, S., Telles, G. D., Zopf, E., Ugrinowitsch, C., & Conceição, M. S. (2020). Aerobic Exercise-Induced Changes in Cardiorespiratory Fitness in Breast Cancer Patients Receiving Chemotherapy: A Systematic Review and Meta-Analysis. Cancers, 12(8), 2240.

McTiernan A. (2004). Physical activity after cancer: physiologic outcomes. Cancer investigation, 22(1), 68-81.

Petersen, A. M., & Pedersen, B. K. (2005). The anti-inflammatory effect of exercise. Journal of applied physiology (Bethesda, Md. : 1985), 98(4), 1154-1162.

Ramos-Goñi, J. M., Craig, B. M., Oppe, M., Ramallo-Fariña, Y., Pinto-Prades, J. L., Luo, N., & Rivero-Arias, O. (2018). Handling Data Quality Issues to Estimate the Spanish EQ-5D-5L Value Set Using a Hybrid Interval Regression Approach. Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research, 21(5), 596-604.

Rosero, I. D., Abel, B., Morilla, I., & Izquierdo, M. (2020). Effects of a Multicomponent Exercise Program in Older Adults with Non-Small-Cell Lung Cancer during Adjuvant/Palliative Treatment: An Intervention Study. Journal of Clinical Medicine, 9(3), 862.

Spence, R. R., Heesch, K. C., & Brown, W. J. (2010). Exercise and cancer rehabilitation: A systematic review. Cancer Treatment Reviews, 36(2), 185-194.